On the night of September 18, 2022, 45-year-old James Loynes was found inside a home in the 1000 block of North Centennial Street in Indianapolis suffering apparent gunshot wounds. Officers from the Indianapolis Metropolitan Police Department responded to a call about 10 p.m.; emergency medical personnel worked at the scene but Loynes was pronounced dead there. The Marion County Coroner later ruled his death a homicide from multiple gunshot wounds.

Detectives with IMPD opened an intensive investigation and issued a public appeal for anyone with information. If anyone knew James, saw activity around North Centennial Street that night, or has information that could help, please share what is known with investigators.