Leona Rodriguez was 16 when she disappeared from Manhattan on August 15, 1991. She is described as a Hispanic female with red or auburn hair and brown eyes, about five feet tall and 115 pounds. The last reported clothing was a blue shirt, blue shorts, and black sneakers.

Details about the circumstances of her disappearance are sparse. The NYPD Missing Persons Squad opened an investigation, created a case file, and her information was entered into national missing persons databases, including NamUs, but investigators have not developed significant leads and the case remains unresolved.

Anyone who knew Leona, her friends, hangouts, or movements in Manhattan in August 1991 is urged to come forward with information that might help explain what happened to her.