Isaac Lopez, also known as Isaac Gomez-Lopez, was a 15-year-old Hispanic/Latino from Phoenix who was killed the night of Wednesday, September 24, 2008, while walking to visit his girlfriend. He was headed toward a bus stop near North 35th Avenue and Roosevelt Street in central Phoenix when two other males confronted him at about 11:15 p.m., chased him into the street, and during or immediately after that chase he was shot. He was found critically wounded, taken to a nearby hospital, and later died from his injuries.

Silent Witness and crime-stoppers listings describe the homicide as unsolved and offer a reward of up to $1,000 for information leading to an arrest or indictment. The motive and the events that precipitated the confrontation have not been publicly explained.

If anyone knew Isaac, was in that neighborhood that night, or has information about the two men who fled, please come forward with tips.