Irina Trache, 44, vanished from her Queens home on or around September 5, 2011. Originally from Romania, she had built a life in New York City and was described as active, responsible and close to a group of friends. She did not show up for work or scheduled appointments, prompting loved ones to report her missing and the NYPD Missing Persons Squad to open an investigation.

Trache was last seen in Midtown Manhattan. A search of her residence did not immediately suggest signs of foul play, and no apparent conflicts in her personal or professional life were reported. Despite searches of places she frequented and wide circulation of her photograph, investigators found few significant leads and the case grew cold. The disappearance remains open and unexplained.

If anyone knew Irina, saw her in early September 2011, or has information that could help, please come forward.