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On the evening of May 15, 2023, a drive-by shooting in the North County Precinct of St. Louis, Missouri, left 34-year-old Casandra Cole dead. She was in the parking lot of a business on the 100 block of Shepley Drive, near the Uptown Market, when a dark-colored vehicle drove west on the street and occupants fired rifle rounds into the crowd. Some people at the scene returned fire at the fleeing car.

Officers found two people with apparent gunshot wounds; Cole was taken to a hospital but died from her injuries. A man at the scene was also shot and expected to survive, and a third victim, another woman, walked to a nearby residence and later received treatment for non-life-threatening wounds. Detectives obtained surveillance footage of the suspect vehicle, but the shooters fled before police arrived.

The St. Louis County Police Crimes Against Persons Bureau has classified the case as an open homicide and is asking anyone with information to contact the department or submit anonymous tips through regional CrimeStoppers. Does anyone have information about the vehicle, occupants, or that night near Shepley Drive?