On February 16, 2023, 28-year-old Humberto Marin-Garcia of Chicago was shot and killed while driving on the Stevenson Expressway (Interstate 55) around 9:20–9:30 p.m., near Ashland Avenue or Lock Street. He was driving with his wife, Mayra Solis, who was about six months pregnant; she was not physically injured by the gunfire but was taken to St. Anthony Hospital as a precaution. Marin-Garcia was pronounced dead at the scene and the shooter fled.

An Illinois State Police review of hours of surveillance footage identified a suspected vehicle and its occupants. On February 26, 2023, Chicago police with the ISP North Statewide Anti-Violence Enforcement group pursued that vehicle; the passengers were taken into custody and 22-year-old Nicholas Samudio was identified as the suspect wanted for questioning in the homicide. Samudio has been indicted for first-degree murder, pleaded not guilty, and is being held without bond; prosecutors have not disclosed a motive.