Francis Muriel Sarah Anne Harris, 45, disappeared from her home on Highway 28 in Apsley, Ontario, on Friday, April 21, 1972. She had accompanied her husband Stanley to a medical appointment in Peterborough that morning; they stopped in Lakefield and arrived home about 11:00 a.m. They had lunch, and Stanley left for work about 1:00 p.m. Their 13-year-old son Rod returned from school at about 3:40 p.m. and found the house empty and his mother gone. Her purse, clothing and family heirlooms remained in the home. She was described as 5 feet 1 inch, about 99 to 100 pounds, short wavy grey or white hair that may have been dyed black, brown eyes, wore glasses and had false teeth. She was thought to be dressed in black slacks, a blouse, a pink cardigan and black pull-on shoes that day.

Authorities have kept the case open and have repeatedly searched the five-acre property, including digs in 2012 and excavations inside and around a barn in November 2023 with cadaver dogs; no evidence has been recovered that advanced the investigation. A forensic age-progression sketch was later released to help generate leads. Stanley Harris died in June 2021 at age 92.

Anyone who knew Francis, her movements that afternoon, or who has information about the Harris property is asked to come forward.