John David Santana, 17, has been missing from Austin, Texas since the summer of 2025. His intended destination that night is unknown, though he was reportedly seen in the South Austin area.

John was 16 at the time of disappearance and is described as an American Indian / Alaska Native male, 5 feet 2 inches tall, weighing 120 to 130 pounds. He has a life-threatening medical condition that requires daily prescription medication and is believed to have left home with only a limited supply. The Travis County Sheriff’s Office is handling the case (phone 854-9770); NCMEC can be reached at 1-800-843-5678 and lists this as Case #2060999 (NCIC# M778549745).

Anyone who knew John, saw him in South Austin that July night, or has information about his medication or movements should contact the Travis County Sheriff’s Office or NCMEC.