Mikalena Nau, 37, was last seen on February 4, 2006, in the Oxford Circle/Castor Gardens area of northeast Philadelphia. Known by her birth name Michelle to some, she had legally changed her name to Mikalena and was living alone while attempting to rebuild her life. On the day she vanished she was seen withdrawing $100 from an ATM near her home and never contacted family again.

Family members who checked her apartment found it in disarray and her dog left behind, prompting a missing-person report. Investigators later found her 1997 Mercedes-Benz several miles from her residence; her purse was recovered nearby but her cell phone was missing. Witnesses said the vehicle had been sitting in that area for an extended period.

Detectives developed a theory after interviews indicated Nau attended a gathering at an apartment the night she disappeared, where witnesses alleged she suffered a medical and physical crisis and died. Authorities say individuals present concealed what happened and that critical evidence was never recovered; one key person tied to the case died shortly afterward in an unrelated homicide. Her remains have never been found and investigators consider recovery extremely unlikely, so she remains listed as missing.

Did anyone who knew Mikalena or who lived in that neighborhood in early February 2006 notice anything unusual around the time she vanished?