Dena Angelique Candelario, 36, vanished from her Pueblo, Colorado home after being last seen on August 15, 2004. A goodbye note was found on a table in the residence. Her husband, Ralph Candelario, did not report her missing until September 6 and told police he thought she may have left voluntarily, possibly to be with someone she met online. The case produced few leads and Dena’s two sons were left without a clear explanation for her disappearance.

Ralph later divorced Dena, married Pamela in 2009, and in January 2015 Pamela was found brutally beaten to death in the couple’s Walsenburg home. Ralph initially said intruders attacked them; investigators did not accept that account. He was arrested, tried, convicted in March 2016 of Pamela’s murder and sentenced to life in prison. That conviction prompted authorities to reopen Dena’s 2004 disappearance. One of Dena and Ralph’s sons has publicly said he believes his father was responsible. No suspect has been officially named in Dena’s case and it remains open.

If anyone knew Dena, her routines in Pueblo, or saw anything around August 15, 2004, can you share information with investigators?