Samantha Neuwein, 35, was found gravely injured inside her Wilmington, Delaware, apartment on the morning of July 12, 2013. Her mother, arriving to open the family appliance shop below the apartment on North Shipley Street, noticed water leaking from the ceiling, went upstairs when there was no answer, and discovered Samantha badly wounded. Responders found stab wounds and signs she had been beaten or bludgeoned; she was taken to Christiana Hospital in critical condition.

Police opened a homicide investigation but released few details about motive, how anyone may have entered the apartment, or what evidence was recovered. Around the same time Wilmington police reviewed another August 2013 fatal stabbing, and the FBI was asked to look for possible similarities, but no confirmed link was announced.

No arrests or named suspects have been publicly reported and the case remained unsolved as investigators continued to seek help from the public. If anyone knew Samantha, her routines, visitors to that building, or saw something on July 11–12, 2013, please come forward with information.