Originally from Pensacola, Florida, she had traveled to Biloxi by bus on September 27, 2008, intending a short visit to the casinos and was last confirmed at the Beau Rivage Casino Resort in the early morning hours of October 4. She spoke by cell phone with one of her children on October 3 and was reported missing by her son after more than a month without contact; the missing-person report was not filed until November 5, 2008.

At the time of her disappearance Tran was described as an Asian female, 5 feet tall, about 140 pounds, with black hair, brown eyes and pierced ears. Law enforcement, including the Biloxi Police Department, has continued to investigate and her case is listed in the Mississippi Repository for Missing and Unidentified Persons. Few leads have been reported and her whereabouts remain unknown.