Regina Bos, a 40-year-old musician and mother of three, vanished after an open mic night at Duggan’s Pub in Lincoln, Nebraska. On the evening of October 16, 2000, witnesses said she was in good spirits; she left the pub around 1:00 a.m. on October 17 after saying she would pick up her boyfriend and then go home. Patrons saw her leave carrying her guitar.

The next morning her car was found parked across the street from Duggan’s with the trunk slightly ajar. Inside were her cherished guitar and sheet music; her purse was missing. Family members say she would never have left her guitar unsecured, and investigators from early on have considered foul play rather than a voluntary disappearance. There were no signs of a struggle at the vehicle, and an early search with dogs produced no leads. The original detective later retired saying he believed he knew who was responsible but lacked evidence to charge anyone.

Her family has continued public outreach with fliers and vigils, yet the case remains unsolved. If anyone who knew Regina, frequented Duggan’s that night, or has information about her movements after she left the pub can help, please come forward.