Margo Nerine Ascencio, 22, was found murdered on March 1, 1975, in a room at the El Don Motel in Eugene, Oregon. She had checked into the motel earlier that evening and was discovered having been stabbed multiple times; the attack is described as particularly violent and she had died of her injuries by the time authorities arrived.

Despite investigations, no significant leads have emerged and the homicide remains unsolved. Eugene police are revisiting cold cases and seeking tips, noting that advances in DNA testing and other investigative methods offer potential avenues for breakthroughs in 1970s cases such as this one.

If anyone has information about Margo Ascencio, her movements that night, or the El Don Motel in March 1975, please contact Eugene police with what you know.