James Henry Mayberry Jr., 35, was last seen in Kenedy, Texas, on April 1, 1999. Known as Jamie and a cross-dresser, he left his home around 11:00 p.m. with an unknown man who had knocked on his door. He told his niece he didn’t know the man but said he would be right back; he was never seen again.

Mayberry was wearing women’s clothing that night — a beige blouse, khaki shorts, and slip-on white shoes — and left behind required medications and his disability payments, his only income. Two men came to the house the next morning looking for him but left after speaking with the niece. Family and investigators think foul play is likely and have suggested the disappearance might have been motivated by bias against his sexual orientation and cross-dressing. A man who had threatened Mayberry the night before left town soon after and was never interviewed.

Anyone who knew Jamie, saw him on April 1, 1999, or has information about the unknown man who knocked on his door is asked to come forward.