Lisa Ann Pierce was 27 when she was last seen on November 6, 2000, at the intersection of Government Boulevard and Pleasant Valley Road in Mobile, Alabama. Her common-law husband reported her missing. She is listed as an endangered missing person and investigators have said she may have been the victim of a homicide, though public details on that theory are limited.

Born August 18, 1973, Lisa was petite at 5 feet 3 inches and about 95 pounds, with sandy brown hair, hazel eyes, pierced ears and a tattoo of the initials RS on her right ankle. She struggled with drug addiction and had placed her children for adoption. In the weeks before she vanished she told her aunt she feared for her life; the aunt attributed those fears to possible paranoia from drug use. A few weeks after Lisa disappeared, a set of keys known to belong to her was mailed to a place she had stayed, with no return address.

Lisa has never been found and no one has been charged. Did anyone in Mobile around November 2000 see Lisa or notice the keys being sent to that address?