Rosario Pacheco-Flores was 28 when she vanished from Phoenix, Arizona. She was last seen around noon on April 7, 2008, leaving her home near West Hatcher Road and 15th Avenue. At that time she was wearing a black shirt, blue jeans, and black sandals. Rosario is described as a Hispanic female with brown hair and brown eyes, pierced ears, a small round blemish on her back, and a tattoo of three flowers on her lower back.

Rosario was last seen in the company of her boyfriend, Luis Fernando Castillo Villafana, who also disappeared and has not been heard from since. The Phoenix Police Department opened an investigation on April 23, 2008, and authorities classify Rosario as an endangered missing person; investigators suspect foul play. Few details have emerged since, leaving the families without answers.

If anyone knew Rosario or Luis, lived in that neighborhood in April 2008, or has information about their whereabouts, please share what you know.