Stacy Renee Lester was 25 when she went missing from Sumter, South Carolina. She was last officially seen on August 9, 2009, at Tuomey Regional Medical Center after a routine medical procedure. She called her mother from the hospital to arrange a ride, but when her sister arrived to pick her up, Stacy was not there and was never seen or heard from again.

Her mother last saw her during the final week of July 2009. Stacy often spent time in south Sumter, around Red Bay Road and Vaughn Street. She is described as a Caucasian female with blue eyes and blond or strawberry-blond hair, sometimes dyed auburn. Distinctive tattoos include a heart with two doves facing away from each other on her chest and another on her ankle; she also had a benign cholesteatoma in her ear. She was believed to be wearing a white t-shirt and denim shorts when last seen.

The case was briefly closed after a mistaken report that she had returned home, but that error was corrected and the investigation was reopened and remains active. If anyone knew Stacy, saw her on or after August 9, 2009, or has information about her whereabouts, please come forward.