Tirrel Santiago was 16 when he disappeared from Brooklyn on the evening of August 20, 2005. He was last seen at about 9:15 p.m., reportedly getting into a cab with an unidentified man. Accounts differ on the exact last-seen spot, placing him either near 306 Rodney Street or near West 10th Street and Hudson Avenue.

Tirrel, also known as Mia, is described as a Black male with black hair and brown eyes, 5 feet 6 inches tall and 115 pounds. He was a student at the Repertory Company High School for Theatre Arts and is transgender, often dressing in women’s clothing. His family reported him missing five days after the sighting, and the NYPD Missing Persons Squad has handled the investigation.

Few public details or significant leads have emerged. Age-progressed images have been circulated in later years in hopes of identification. If anyone knew Tirrel, saw him around August 20, 2005, or can identify the man he got into a cab with, please come forward with information.