Refugio Isaguirre, an 81-year-old man from Seguin, Texas, was last seen on January 5, 1992. He had Alzheimer’s disease and epilepsy and was reportedly seen on San Antonio Street in Seguin at about 6:00 p.m. that evening. He was wearing a long-sleeved light-colored shirt, tan or brown pants, house slippers or shoes, and a white hat.

His medical needs included medication four times a day, which made his disappearance especially worrying. The case is classified as endangered and remains open. It is listed in NamUs, and the Seguin Police Department has asked anyone with information to come forward.

Are there any witnesses or neighbors from Seguin who remember seeing Refugio that night or who might have information that could help his family find answers?