Rayshaun Cotton was 29 when he was shot while driving on Holloway Street in Durham, North Carolina, on March 8, 2010. After being struck by gunfire, his vehicle collided with a tree; he was taken to Duke University Hospital and died of his injuries two days later. The killing was one of 25 homicides in Durham that year and remains unsolved.

In September 2010 the Religious Coalition for a Nonviolent Durham held a prayer vigil for Cotton, where red balloons were released in his memory and family and community members gathered to grieve. His mother, Betty Cotton, is described as taking each day one at a time as she seeks closure.

Anyone with information about the shooting is asked to contact Durham CrimeStoppers.