Mathew Colter, 46, was last seen at his home on Erika Road in Orangeburg, South Carolina, in the early evening of November 17, 2003. His sister was the last person to see him around 6:30 p.m. and later described his behavior that night as unusual. Colter lived with schizophrenia and required medication; none of his medication was with him when he vanished.

The following day his sister returned and found the back door unlocked with pry marks, damaged appliances, and human feces on the floor and a bed. There was no sign of Mathew. Searches that included bloodhounds and aerial support turned up no confirmed sightings, and a few reported leads could not be verified. Authorities have treated the scene as suspicious and the investigation remains open and unsolved.

Does anyone who lived in Orangeburg in November 2003 remember seeing Mathew or anything unusual near Erika Road that night?