Lillian May Mathis, 26, was last definitively seen in March 2010 when she traveled from Winston-Salem, North Carolina, to Columbia, South Carolina. She is described as having blonde hair and blue eyes and is known by the nickname Lilly Sears. A distinctive smiley face tattoo burned into her right bicep is a notable identifying feature.

The reasons for the trip to Columbia and how long she intended to stay are unknown. The timeline after her arrival is hazy; there was a possible but unconfirmed sighting of her in Winston-Salem in November 2010, but details about that sighting are scarce. The Winston-Salem Police Department is the investigating agency and the case remains open.

If anyone knew Lillian, her routines, who she traveled with, or saw her in Columbia or Winston-Salem in 2010, please share information with the Winston-Salem Police Department.