On the night of October 14, 2025, 40-year-old Joseph Castillo was shot near the intersection of Midland Avenue and West Brighton Avenue in Syracuse. Police found him about 11 p.m. with multiple gunshot wounds to his head, arm, and back; he was taken to Upstate University Hospital and pronounced dead from his injuries.

Syracuse police identified 41-year-old Lakeeyah May as the person allegedly responsible and took her into custody without incident on West Brighton Avenue, not far from the shooting. Officers also found a red pickup truck that had crashed into a utility pole near the scene. May has been charged with second-degree murder and is being held at the Onondaga County Justice Center awaiting arraignment. The investigation remains active.

Anyone with information about the shooting or who saw activity in the Midland and West Brighton area on October 14 is asked to contact the Criminal Investigations Division.