Jacqueline Diane Lombardi was 22 when she left her home in the Surrey Hill neighborhood of Howland Township, Ohio, on March 19, 2011. Concerned friends and family reported she struggled with substance abuse and faced outstanding warrants for theft and drug-related charges. She split her time between the Warren area and Painesville, Ohio.

When she disappeared she was wearing a tie-dye coat and brown-to-pink framed glasses. She had brown hair, brown eyes, pierced ears and a tattoo of a chain with Italian writing on her right foot. The last confirmed sighting was shortly after she left home in Warren. An extensive investigation by the Howland Township Police Department went cold, and few details were made public for years.

In March 2020 the Howland Police Department and the U.S. Marshals Service reopened the file and identified some people Jacqueline visited after leaving that day, but investigators say they need more information. If anyone knew Jacqueline, saw her on or after March 19, 2011, or has information about the people she visited, please come forward.