Cynthia Renea Milstead was last seen in San Francisco on January 8, 2001, when she left a friend’s residence near 16th Street and Mission Street between 2:00 a.m. and 3:00 a.m. She was 20 at the time and would have been especially vulnerable: she was mentally disabled, functioned at the intellectual level of an eight‑ to twelve‑year‑old, was illiterate and only able to sign her name, and did not have a driver’s license or any driving experience.

At disappearance she was about 5 feet 3 inches and 120 pounds, with blonde or strawberry‑colored hair and blue eyes. Distinctive features included burn scars on her forearms, a strawberry‑colored birthmark on the nape of her neck, pierced ears, a chipped upper front tooth, a previously fractured thumb, and a diamond ring noted on her right hand. She also suffered from epilepsy and a heart condition and may have required medication.

The San Francisco Police Department classified her as an endangered missing person (case number 05‑0553300), and she is listed in NamUs as MP 19569. Few details are available about what happened after she left the friend’s house and there have been no confirmed sightings reported. Anyone with information is asked to contact the San Francisco Police Department and reference case number 05‑0553300 or NamUs MP 19569.