On the evening of November 17, 2009, police in the Jeff-Vander-Lou neighborhood of North St. Louis found 29-year-old Mario Resean Williams around 9:30 p.m. He was an African-American man who had sustained multiple gunshot wounds; his death was ruled a homicide. The location is described as an area that experienced frequent violent crime at the time.

The St. Louis Metropolitan Police Department Homicide Division worked the initial investigation and sought witnesses, but the case produced no significant leads. No arrests or suspects have been publicly identified, and the investigation is cold. Anyone who may have information about what happened that night is asked to contact the Homicide Division or submit a tip through CrimeStoppers.