Regina Powell was a 53-year-old woman from Portsmouth, Ohio, who died on July 4, 2000. Initial reports described her death as unclear, and a local investigation eventually determined she had been murdered.

The case later involved a suspect from southern Ohio, Darryl L. Walters, who confessed to Powell’s murder and to the killings of two other women. DNA evidence was reported to have linked that suspect to the scene, and he was arrested and charged in connection with Powell’s death.

The killing devastated Powell’s family and the Portsmouth community. If anyone knew Regina, saw her that weekend, or has information about her last movements, please share what is known.