Giselle Lopez was 19 when she was fatally shot on September 5, 2018, outside her home in Garfield Heights, Cleveland. A recent graduate of Garfield Heights High School who had been studying nursing at Cuyahoga Community College, she was described as kind, humble, and dedicated to her studies. Her parents are Manuel Lopez and America Polanco; she was the sister of Roberto Lopez and the late Manuel Lopez.

Manuel Lopez Jr., 17, intervened and Nicholson threatened to kill everyone present. As Giselle and Manuel attempted to leave, Nicholson stepped outside and fired multiple shots, killing both teenagers. Giselle was taken to a hospital and died after emergency surgery; Manuel was pronounced dead at the scene. Nicholson, a private security officer, was arrested after a four-hour standoff and charged with two counts of murder and three counts of domestic violence.

The loss affected family and the school community deeply.