Sheila St. Clair, a 48-year-old Native American woman, was last seen on August 20, 2015, in Duluth, Minnesota, reportedly at the Cascade Apartments in the Central Hillside neighborhood. She told people she planned to travel to the White Earth Reservation or possibly to Red Cliff, Wisconsin, but never arrived at either place. She was not reported missing until September 10, 2015.

At the time she disappeared Sheila did not own a vehicle and may have been relying on others for transportation. She had health issues and walked with a limp from a crippled right foot. She was last seen wearing a black sleeveless dress and light-colored shoes and had a distinctive eagle tattoo on her right arm; she often used the last name Jackson. Her disappearance is described as highly suspicious and uncharacteristic.

Despite extensive searches and ongoing investigations, the case remains unsolved and her family and community continue holding vigils. If anyone saw Sheila around August 20, 2015, or remembers seeing someone fitting her description between Duluth and the White Earth Reservation or Red Cliff, Wisconsin, contact investigators.