Tyree Smith, a 40-year-old African American man, was shot and killed in East Saint Louis, Illinois, on February 4, 2015. He was found with multiple gunshot wounds after what investigators described as a drive-by shooting; witnesses reported hearing multiple gunshots and seeing a vehicle speed away from the scene. The case initially stalled partly because potential witnesses were reluctant to cooperate.

Police later developed enough evidence to arrest several suspects. Two teenagers at the time, Demaurion Moore and Mekhi Cable, were charged with first-degree murder and related offenses. The prosecution said the shooting was premeditated and tied the suspects to gang activity. Both defendants were tried, convicted, and sentenced to lengthy prison terms.

The killing highlighted concerns about gang-related violence in East Saint Louis and the difficulty of securing witness cooperation. If anyone knew Tyree Smith, or has information about the events of February 4, 2015, please come forward.