Gabriel Lopez, a 45-year-old Hispanic man, was last seen in Chicago, Illinois, on January 27, 2006. His family reported him missing to the Chicago Police Department on January 29, 2006; the case was assigned to Area Central as HM-151897. At the time he disappeared he was described as between 5 feet 10 inches and 5 feet 11 inches tall, weighing between 250 and 260 pounds, with black hair and brown eyes.

Investigators had few concrete leads. One unverified theory is that Gabriel may have traveled to Texas or to Mexico, but no evidence has been produced to confirm travel or his whereabouts. There is no record in the material of what clothing or personal items he had when last seen. His case was entered into NamUS on June 22, 2017, as MP38761 to broaden the search.

Anyone who knew Gabriel, remembers seeing him in late January 2006, or has information about travel to Texas or Mexico is asked to come forward.