Darlene Fleshman, a 42-year-old woman from Union, West Virginia who used her middle name, went missing after leaving home on September 15, 2012, reportedly heading for Roanoke, Virginia. She was last seen at the Apple Valley Motel in Roanoke on September 8, 2012; her belongings were recovered there but neither she nor her 1994 Chevrolet Cavalier with West Virginia plates has been found since.

Darlene is described as having brown hair, brown eyes, extensive freckles, and wearing eyeglasses. She had multiple piercings, including nose and navel, and suffered from diabetes and seizures, which is why her disappearance is classified as endangered. Both Virginia and West Virginia authorities have been involved in the investigation, but few leads have emerged and the case remains unsolved.

If anyone saw Darlene, her Cavalier, or has information about her movements in early September 2012 around Roanoke or the Apple Valley Motel, please come forward with what you know.