Jorge Fernando Casillas was 28 when he was shot and killed on the night of March 7–8, 2008, on the block of 3500 E. Siskiyou Street in Los Angeles, near Boyle Heights. According to investigators, he had just arrived home and exited his vehicle when several Latino men approached and one shot him in the back with a shotgun. He was taken to County‑USC Medical Center and pronounced dead at 12:31 a.m. on March 8.

The LAPD Rampart Division handled the investigation. Detective Scott Smith said the suspects fled immediately after the shooting, the motive was unclear, and there were no arrests. The case remains unsolved and investigators urged anyone with information to come forward.