Madison R. Weiss was 28 when she was shot and killed in Downtown Los Angeles on August 23, 2021. Medical Examiner–Coroner records place the shooting near 839 S. Los Angeles St., in the early morning hours; she was transported to a nearby hospital but died shortly after arrival. Reports indicate she was shot multiple times, and witnesses heard gunfire and saw a vehicle speed away from the scene.

The LAPD treated the case as a targeted attack and identified several persons of interest, conducting numerous interviews. Investigators faced challenges from limited physical evidence and some witnesses reluctant to come forward. In the months after the killing, police arrested a suspect who was charged with murder and related offenses, and legal proceedings were underway.

Anybody who remembers hearing shots or saw a vehicle leaving the area that morning, or who has other information about Madison, is asked to come forward.