Reginald Hamilton, a 35-year-old Black man from North Charleston, South Carolina, was shot and killed in the Economy Inn parking lot on Rivers Avenue in the early hours of October 20, 2021. Police were called for reports of shots fired around 1 a.m.; officers found a man unresponsive in the motel lot who was later identified by the coroner as Hamilton. The scene was processed with numbered evidence markers while detectives from the North Charleston Police Department and the Charleston County Coroner’s Office investigated. No arrests had been announced in the immediate aftermath and the killer remained at large.

Hamilton’s death was later noted in local obituaries handled by Dickerson Mortuary and on an online memorial for victims of gun violence, where friends and family left condolences and virtual candles. On November 19, 2021, authorities announced an arrest: 45-year-old Sean D. Brown was taken into custody and charged with murder and weapons offenses; the U.S. Marshals Task Force assisted and Brown was booked into the Al Cannon Detention Center. If anyone knew Reginald or saw activity outside the Economy Inn that night, please share what might help fill in the timeline.