Kayla Jo Hamby was 33 when she was found with a life‑threatening gunshot wound inside a room at the InTown Suites on Cinema Center in Anderson, South Carolina, on the evening of March 22, 2022. Emergency crews transported her to AnMed Health Medical Center and she was later airlifted to Prisma Health Greenville Hospital. On March 24, 2022, she was pronounced brain dead and remained on life support to allow for organ donation. The Anderson County Coroner’s Office ruled her death a homicide.

Investigators say the initial call reported a possible suicide attempt, but evidence and witness interviews led detectives to focus on Hamby’s husband, Keenan Trentle Anderson, who was present in the motel room. He was arrested and charged with murder and with possession of a weapon during a violent crime. At trial the prosecution presented crime scene evidence and witness testimony; a jury convicted Keenan Anderson of murder and he received a 35‑year term with an additional five years for the weapons charge, to be served concurrently.

If anyone knew Kayla, her movements that week, or has information about the motel room that night, please share what is known.