Clifton Southern, 44, was shot and killed in the early evening of November 5, 2021, in the Old North St. Louis neighborhood. Officers responding just after 6 p.m. found him at the 2800 block of North Florissant Avenue, near a Shell gas station; he had been shot in the face and was pronounced dead at the scene. The St. Louis Metropolitan Police Department classified the death as a homicide and opened an investigation.

Despite investigative efforts in the days and weeks afterward, reports did not identify a motive or name any suspects, and no arrests were announced. The community and his family were left without answers as the case remained unresolved. If anyone has information about what happened that evening or knew Clifton Southern, please come forward with tips for investigators.